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IL-6 had a sensitivity of 81.5% and a specificity of 81.8% with a cut-off value of 37.5. On multivariable logistic regression, CT severity score, NIPPV, and IL-6 had an odds ratio of 1.17, 0.052, and 1.03, respectively. The leucocyte count, C-reactive protein (CRP), urea, creatinine, interleukin-6 (IL-6), and lactate dehydrogenase (LDH) were greater, and platelet counts were lower significantly in the non-survivors group. The common symptoms were fever, respiratory distress, cough, muscle pain, and sore throat. The mean age was significantly greater in non-survivors. Patient’s management and treatment outcomes as survivors and non-survivors were noted. Computed tomography severity score (CTSS) and hematological and inflammatory parameters at the time of admission were noticed. The patient’s symptomatology, vital signs, oxygen saturation (Spo2), need for inotropes, and non-invasive positive pressure ventilator support (NIPPV) were observed. The patient’s age, gender, and co-morbidities like type 2 diabetes mellitus, hypertension, respiratory illness, and coronary artery disease were noted. A total of 125 patients above 18 years were included in the study.
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This retrospective study was done in patients admitted to intensive care units for COVID-19 with a positive reverse transcriptase polymerase chain reaction (RTPCR) assay. The current study aimed to determine the association of clinical and inflammatory profiles with the outcome of COVID-19 infection in patients admitted to the intensive care unit. It is crucial to comprehend sickness severity and outcome predictors to provide early preventative measures for a better outcome. The complex interactions between the host, virus, and environment have resulted in various clinical outcomes. The coronavirus disease (COVID-19) pandemic has incurred high costs for the entire planet.
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